Please use this identifier to cite or link to this item: https://idr.l1.nitk.ac.in/jspui/handle/123456789/13292
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dc.contributor.authorVijesh, A.M.-
dc.contributor.authorIsloor, A.M.-
dc.contributor.authorPrabhu, V.-
dc.contributor.authorAhmad, S.-
dc.contributor.authorMalladi, S.-
dc.date.accessioned2020-03-31T08:45:32Z-
dc.date.available2020-03-31T08:45:32Z-
dc.date.issued2010-
dc.identifier.citationEuropean Journal of Medicinal Chemistry, 2010, Vol.45, 11, pp.5460-5464en_US
dc.identifier.urihttp://idr.nitk.ac.in/jspui/handle/123456789/13292-
dc.description.abstractIn the present study a series of novel 2,4-disubstituted thiazole derivatives containing substituted pyrazole moiety was synthesized by the reaction of 3-Aryl-1H-pyrazole-4-carbaldehyde thiosemicarbazone with 6-Bromo/H-3-(bromoacetyl)-2H-chromen-2-one/phenacyl chloride. Structures of newly synthesized compounds were characterized by spectral studies. New compounds were screened for their antibacterial studies against Staphylococcus aureus, Bacillus subtilis, Escherichia coli and Pseudomonas aeruginosa. The results revealed that compounds 7c, 8e, and 8f having 2,5-dichlorothiophene substituent and 8c, 8d having 2,4-dichlorophenyl substituent showed significant antibacterial activity against all tested microorganisms. 2010 Elsevier Masson SAS. All rights reserved.en_US
dc.titleSynthesis, characterization and anti-microbial studies of some novel 2,4-disubstituted thiazolesen_US
dc.typeArticleen_US
Appears in Collections:1. Journal Articles

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