Please use this identifier to cite or link to this item: https://idr.l1.nitk.ac.in/jspui/handle/123456789/9610
Title: A highly efficient and green cascade synthesis of 3-methyl-substituted-4- hydroxy-1-methyl-quinolin-2(1H)-ones under solvent- and catalyst-free conditions
Authors: Bhat, S.I.
Trivedi, D.R.
Issue Date: 2014
Citation: RSC Advances, 2014, Vol.4, 22, pp.11300-11304
Abstract: An expeditious and green protocol for the synthesis of 3,3?- methanediylbis(4-hydroxy-1-methylquinolin-2(1H)-one) (MDBHQ) derivatives and 3-((2-amino-6-oxocyclohex-1-enyl)methyl)-4-hydroxy-1-methylquinolin-2(1H)-one (AOCHQ) derivatives has been developed via a cascade Knoevenagel-Michael reaction. The products were obtained in high yield under neat reaction conditions without any work-up or chromatographic purification. The generality and functional tolerance of this environmentally benign protocol is demonstrated. 2014 The Royal Society of Chemistry.
URI: 10.1039/c3ra45208e
http://idr.nitk.ac.in/jspui/handle/123456789/9610
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